Joanna of Castile, aka Joanna the Mad, was the first queen to reign both Castile and Aragon at the same time. She was known for Joanna the Mad because of her mental illness. She was the 3rd child born to Isabella of Castile and Ferdinand of Aragon. She was also the elder sister of Queen Katherine of Aragon, King Henry the VIII's first wife. She was a very attractive young woman and married Philip of Castile in 1496. She gave birth to 6 children. Joanna suffered from a mental illness known as Schizophrenia. She died in 1555 at age 75.